Research

Deep brain stimulation (DBS) is an established treatment for late motor symptoms in Parkinson’s disease (PD). Although DBS is generally a successful therapy, it has limitations including insufficient clinical effects and adverse side effects. The effect of DBS and disease progression is reflected by modulation of cerebral bioelectrical activity that can be measured by electrophysiological studies. The long-term clinical outcome for PD patients with DBS does not depend exclusively on the efficacy of the DBS therapy.

Over the last almost twenty years, there has been a continuous search for a method of pacing that can avoid adverse left ventricular (LV) remodeling and heart failure. Both apical and right ventricular (RV) septal pacing were found to have similar clinical outcomes, in as much as they both lead to dyssynchronous ventricular contractions. Patients exhibiting substantial ventricular dyssynchrony during pacing are at the highest risk of adverse LV remodeling.

Motion of an optically levitated nanoparticle in high vacuum is sufficiently well isolated from a room temperature environment. Together with recently developed method of cavity cooling by coherent scattering, it has allowed the collaborating group from Vienna to achieve ground state cooling of the nanoparticle motion with an optical cavity, paving the way toward further experiments with nanoparticles in the quantum regime.

The aim of the proposed project is to develop new technologies for the LiteScope device ™ expanding its imaging capabilities with functionalities that will attract new users-customers and help Nenovision to establish itself in developed foreign markets. Three areas have been identified that will allow the necessary technological and commercial advantage to be obtained.

The project addresses design, development and use of physical methods for research of microbial pathogens and their interactions with the environment. The metabolic processes of these microorganisms are regulated by various influences, such as oxygen availability, temperature, culture age, the presence of biofilm, other bacterial species, bacteriophages, or antimicrobial drugs. These interactions remain largely unexplored due to lack of techniques that would allow long-term non-destructive chemical analysis of individual cells under strictly regulated conditions.