Research

TSCAC Two-species composite atomic clocks

This project will explore new techniques and methods to provide novel primary measurement standards for time and frequency. While today’s best optical clocks rely on the use of a single atomic reference transition, this project will investigate two-species composite atomic clocks that improve in terms of accuracy and frequency instability. The project fosters collaboration between leading scientists in the field with complementary expertise from NMIs, universities and research institutes.

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Subcortical nuclei and cortical functions – insight from the deep brain stimulation perspective

Exact knowledge of the role of the subcortical nuclei and their cortical relations in physiological and pathophysiological conditions still remains insufficiently explained. Deep brain stimulation (DBS) is an established treatment for late motor symptoms in Parkinson’s disease (PD) and provides an opportunity to study such interactions, mainly via direct intracranial recording of local field potentials. Surface HDEEG method (high- density EEG) in combination with source reconstruction algorithms represents a new approach to study the impact of DBS on whole brain networks functioning.

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Advanced building elements for automated quality control at Factory 4.0

The project aims to develop a set of new purpose-built design nodes for efficient automation in the manufacturing of components for the automotive, fine mechanics and optics. The set incorporates an ultra-precise laser system for the dimensional inspection of manufactured parts and calibration the object shapes in a meter-length range. This focus is a response to market developments over the past three years, where experienced workers are dwindling, while the demand for more accurate and faster production control with cost savings is growing.

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Optical forces acting on plasmonic nanoparticles as a tool for SERS bioassays fabrication

The aim of this project is to develop a simple, sensitive, precise bioassay for detection of microbial samples. This sensor will be fabricated on the base of optical manipulation and Raman tagging. Optical manipulation of metalnanoparticles is of particular interest in view of the potential applications in biomolecular sensing by surface enhanced Raman spectroscopy (SERS).

English

Non-invasive ventricular electrical activation mapping – 3D VDI mapping

The 3D VDI mapping project aims to research, develop, and implement a highly innovative diagnostic device for non-invasive mapping of electrical activation of heart ventricles. The 3D VDI mapping project's principal added value is the use of the new principle of ultra-high-frequency ECG combined with an extended set of chest electrodes. The result will be an easy-to-apply chest strap electrode configuration and original analysis. There is currently no comparable technology. The commercial potential of VDI mapping is remarkably high worldwide.

English

Methodological research on advanced electron microscopy in microbiology and ecology

The project is focused on the instrumental and methodological research in the field of advanced electron microscopic (EM) techniques beneficial in the morphological studies of microbiological systems with biotechnological potential. Improved methods of sample preparation and microscopic analysis will be applied in the current research on selected microorganisms that are exposed to various stressors including chemical as well as physical action.

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DEEP BRAIN PHOTONIC TOOLS FOR CELL-TYPE SPECIFIC TARGETING OF NEURAL DISEASES

DEEPER aims at tackling this fundamental challenge by developing an entire new class of photonic tools for imaging and manipulating neuronal activity in the deep brain with unprecedented penetration depth, resolution, sensitivity, specificity and depth of focus.

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Clock Network Services - Design Study

The proposed project aims to establish a pan-European time and frequency reference system as a European Research Infrastructure to serve the European science community. It is based on transmitting ultra precise time and frequency information via optical fiber. The proposed project builds on several joint European projects and its direct precursor project CLONETS. We now go far beyond previous efforts by designing a sustainable, pan-European, ultra-precise time-and-frequency reference-system available to the European research community.

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Laserové zdroje záření a metrologie optických soustav v DUV spektrální oblasti

The main goal of the project is to create custom laser source at 266 nm and 213 nm in collaboration with Institute of Scientific Instruments of the CAS and to adapt metrology background and methods mainly to the wavelengths 213 nm and 193 nm for further application in Meopta-optika, s.r.o. production.

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